Inhibition of dendritic cell migration by transforming growth factor-β1 increases tumor-draining lymph node metastasis

BACKGROUND: Transforming growth factor (TGF)-β is known to be produced by progressor tumors and to immobilize dendritic cells (DCs) within those tumors. Moreover, although TGF-β1 has been shown to promote tumor progression, there is still no direct, in vivo evidence as to whether TGF-β1 is able to d...

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Hauptverfasser: Imai, Kazuhiro, Minamiya, Yoshihiro, Koyota, Souichi, Ito, Manabu, Saito, Hajime, Sato, Yusuke, Motoyama, Satoru, Sugiyama, Toshihiro, Ogawa, Jun-ichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3298529/
https://ncbi.nlm.nih.gov/pubmed/22233831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-31-3
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