ATR maintains select progenitors during nervous system development

The ATR (ATM (ataxia telangiectasia mutated) and rad3-related) checkpoint kinase is considered critical for signalling DNA replication stress and its dysfunction can lead to the neurodevelopmental disorder, ATR-Seckel syndrome. To understand how ATR functions during neurogenesis, we conditionally de...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lee, Youngsoo, Shull, Erin RP, Frappart, Pierre-Olivier, Katyal, Sachin, Enriquez-Rios, Vanessa, Zhao, Jingfeng, Russell, Helen R, Brown, Eric J, McKinnon, Peter J
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2012
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3298000/
https://ncbi.nlm.nih.gov/pubmed/22266795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.493
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