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A molecular mechanism that links Hippo signalling to the inhibition of Wnt/β-catenin signalling

The Hippo signalling pathway has emerged as a key regulator of organ size, tissue homeostasis, and patterning. Recent studies have shown that two effectors in this pathway, YAP/TAZ, modulate Wnt/β-catenin signalling through their interaction with β-catenin or Dishevelled, depending on biological con...

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Detalhes bibliográficos
Main Authors: Imajo, Masamichi, Miyatake, Koichi, Iimura, Akira, Miyamoto, Atsumu, Nishida, Eisuke
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297994/
https://ncbi.nlm.nih.gov/pubmed/22234184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.487
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