Circadian rhythms govern cardiac repolarization and arrhythmogenesis

Sudden cardiac death exhibits diurnal variation in both acquired and hereditary forms of heart disease (1, 2), but the molecular basis is unknown. A common mechanism that underlies susceptibility to ventricular arrhythmias is abnormalities in the duration (e.g. short or long QT syndromes, heart fail...

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Main Authors: Jeyaraj, Darwin, Haldar, Saptarsi M., Wan, Xiaoping, McCauley, Mark D., Ripperger, Jürgen A., Hu, Kun, Lu, Yuan, Eapen, Betty L., Sharma, Nikunj, Ficker, Eckhard, Cutler, Michael J., Gulick, James, Sanbe, Atsushi, Robbins, Jeffrey, Demolombe, Sophie, Kondratov, Roman V., Shea, Steven A., Albrecht, Urs, Wehrens, Xander H.T., Rosenbaum, David S., Jain, Mukesh K.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297978/
https://ncbi.nlm.nih.gov/pubmed/22367544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10852
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