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Outgrowth of Single Oncogene-expressing Cells from Suppressive Epithelial Environments

Tumorigenesis is a clonal evolution process initiated from single cells within otherwise histologically normal tissue(1). How single, sporadic mutant cells that have sustained oncogenic alterations evolve within tightly regulated tissue environment remains elusive. Here, we investigated the effects...

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Bibliografische gegevens
Hoofdauteurs: Leung, Cheuk T., Brugge, Joan S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297969/
https://ncbi.nlm.nih.gov/pubmed/22318515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10826
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