Uptake of plasma fibrinogen into the alpha granules of human megakaryocytes and platelets.

The origin of platelet alpha-granule fibrinogen (Fg), whether from endogeneous synthesis or exogeneous derivation, remains unknown. Although Fg biosynthesis by megakaryocytes (MK) has been suggested, recent studies have demonstrated that certain alpha-granular proteins originate primarily from plasm...

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Pubblicato in:	J Clin Invest
Autori principali:	Harrison, P, Wilbourn, B, Debili, N, Vainchenker, W, Breton-Gorius, J, Lawrie, A S, Masse, J M, Savidge, G F, Cramer, E M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329793/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2677051/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114300
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