Molecular characterization of antithrombin III (ATIII) variants using polymerase chain reaction. Identification of the ATIII Charleville as an Ala 384 Pro mutation.

The genes of seven structural mutants of antithrombin III (ATIII), presenting either defective serine protease reactivity or abnormal heparin binding, were analyzed. The polymerase chain reaction (PCR) was used to amplify the corresponding gene exon and the mutation was identified by either dot blot...

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Main Authors: Molho-Sabatier, P, Aiach, M, Gaillard, I, Fiessinger, J N, Fischer, A M, Chadeuf, G, Clauser, E
格式: Artigo
語言:Inglês
出版: 1989
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC329783/
https://ncbi.nlm.nih.gov/pubmed/2794060
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