Molecular characterization of antithrombin III (ATIII) variants using polymerase chain reaction. Identification of the ATIII Charleville as an Ala 384 Pro mutation.

The genes of seven structural mutants of antithrombin III (ATIII), presenting either defective serine protease reactivity or abnormal heparin binding, were analyzed. The polymerase chain reaction (PCR) was used to amplify the corresponding gene exon and the mutation was identified by either dot blot...

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Detalhes bibliográficos
Main Authors: Molho-Sabatier, P, Aiach, M, Gaillard, I, Fiessinger, J N, Fischer, A M, Chadeuf, G, Clauser, E
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC329783/
https://ncbi.nlm.nih.gov/pubmed/2794060
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