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Minimal ensembles of side chain conformers for modeling protein-protein interactions

The goal of this paper is to reduce the complexity of the side chain search within docking problems. We apply six methods of generating side chain conformers to unbound protein structures, and determine their ability of obtaining the bound conformation in small ensembles of conformers. Methods are e...

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Detalles Bibliográficos
Main Authors: Beglov, Dmitri, Hall, David R., Brenke, Ryan, Shapovalov, Maxim V., Dunbrack, Roland L., Kozakov, Dima, Vajda, Sandor
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297704/
https://ncbi.nlm.nih.gov/pubmed/22105850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.23222
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