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Novel therapies for metastatic renal cell carcinoma: Efforts to expand beyond the VEGF/mTOR signaling paradigm

With 6 agents approved for metastatic renal cell carcinoma (mRCC) within the past 5 years, there has undoubtedly been progress in treating this disease. However, the goal of cure remains elusive, and the agents nearest approval (ie axitinib and tivozanib) abide by the same paradigm as existing drugs...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pal, Sumanta Kumar, Williams, Stephen, Josephson, David Y., Carmichael, Courtney, Vogelzang, Nicholas J., Quinn, David I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297694/
https://ncbi.nlm.nih.gov/pubmed/22351744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-11-0806
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