CD40L Deficiency Attenuates Diet-Induced Adipose Tissue Inflammation by Impairing Immune Cell Accumulation and Production of Pathogenic IgG-Antibodies

BACKGROUND: Adipose tissue inflammation fuels the metabolic syndrome. We recently reported that CD40L – an established marker and mediator of cardiovascular disease – induces inflammatory cytokine production in adipose cells in vitro. Here, we tested the hypothesis that CD40L deficiency modulates ad...

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Hauptverfasser: Wolf, Dennis, Jehle, Felix, Ortiz Rodriguez, Alexandra, Dufner, Bianca, Hoppe, Natalie, Colberg, Christian, Lozhkin, Andrey, Bassler, Nicole, Rupprecht, Benjamin, Wiedemann, Ansgar, Hilgendorf, Ingo, Stachon, Peter, Willecke, Florian, Febbraio, Mark, Binder, Christoph J., Bode, Christoph, Zirlik, Andreas, Peter, Karlheinz
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297623/
https://ncbi.nlm.nih.gov/pubmed/22412980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033026
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