The noncalcemic analogue of vitamin D, 22-oxacalcitriol, suppresses parathyroid hormone synthesis and secretion.

1,25-Dihydroxyvitamin D (1,25-(OH)2D3) directly suppresses the secretion and synthesis of PTH in vivo and in cell culture. This compound has been used to treat secondary hyperparathyroidism associated with renal failure, but in some patients prolonged treatment with 1,25-(OH)2D3 results in hypercalc...

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Bibliografiska uppgifter
Huvudupphovsmän: Brown, A J, Ritter, C R, Finch, J L, Morrissey, J, Martin, K J, Murayama, E, Nishii, Y, Slatopolsky, E
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1989
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC329712/
https://ncbi.nlm.nih.gov/pubmed/2760211
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