The noncalcemic analogue of vitamin D, 22-oxacalcitriol, suppresses parathyroid hormone synthesis and secretion.

1,25-Dihydroxyvitamin D (1,25-(OH)2D3) directly suppresses the secretion and synthesis of PTH in vivo and in cell culture. This compound has been used to treat secondary hyperparathyroidism associated with renal failure, but in some patients prolonged treatment with 1,25-(OH)2D3 results in hypercalc...

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Détails bibliographiques
Auteurs principaux: Brown, A J, Ritter, C R, Finch, J L, Morrissey, J, Martin, K J, Murayama, E, Nishii, Y, Slatopolsky, E
Format: Artigo
Langue:Inglês
Publié: 1989
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC329712/
https://ncbi.nlm.nih.gov/pubmed/2760211
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