The noncalcemic analogue of vitamin D, 22-oxacalcitriol, suppresses parathyroid hormone synthesis and secretion.

1,25-Dihydroxyvitamin D (1,25-(OH)2D3) directly suppresses the secretion and synthesis of PTH in vivo and in cell culture. This compound has been used to treat secondary hyperparathyroidism associated with renal failure, but in some patients prolonged treatment with 1,25-(OH)2D3 results in hypercalc...

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Bibliographische Detailangaben
Hauptverfasser: Brown, A J, Ritter, C R, Finch, J L, Morrissey, J, Martin, K J, Murayama, E, Nishii, Y, Slatopolsky, E
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1989
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC329712/
https://ncbi.nlm.nih.gov/pubmed/2760211
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