The noncalcemic analogue of vitamin D, 22-oxacalcitriol, suppresses parathyroid hormone synthesis and secretion.

1,25-Dihydroxyvitamin D (1,25-(OH)2D3) directly suppresses the secretion and synthesis of PTH in vivo and in cell culture. This compound has been used to treat secondary hyperparathyroidism associated with renal failure, but in some patients prolonged treatment with 1,25-(OH)2D3 results in hypercalc...

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Detalles Bibliográficos

Publicado en:	J Clin Invest
Principais autores:	Brown, A J, Ritter, C R, Finch, J L, Morrissey, J, Martin, K J, Murayama, E, Nishii, Y, Slatopolsky, E
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Clinical Investigation 1989
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329712/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2760211/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114229
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