Statins and Pulmonary Fibrosis: The Potential Role of NLRP3 Inflammasome Activation

Rationale: The role of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) in the development or progression of interstitial lung disease (ILD) is controversial. Objectives: To evaluate the association between statin use and ILD. Methods: We used regression analyses to evaluate the...

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Main Authors: Xu, Jin-Fu, Washko, George R., Nakahira, Kiichi, Hatabu, Hiroto, Patel, Avignat S., Fernandez, Isis E., Nishino, Mizuki, Okajima, Yuka, Yamashiro, Tsuneo, Ross, James C., San José Estépar, Raúl, Diaz, Alejandro A., Li, Hui-Ping, Qu, Jie-Ming, Himes, Blanca E., Come, Carolyn E., D'Aco, Katherine, Martinez, Fernando J., Han, MeiLan K., Lynch, David A., Crapo, James D., Morse, Danielle, Ryter, Stefan W., Silverman, Edwin K., Rosas, Ivan O., Choi, Augustine M. K., Hunninghake, Gary M.
Format: Artigo
Language:Inglês
Published: American Thoracic Society 2012
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297101/
https://ncbi.nlm.nih.gov/pubmed/22246178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201108-1574OC
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