Statins and Pulmonary Fibrosis: The Potential Role of NLRP3 Inflammasome Activation

Rationale: The role of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) in the development or progression of interstitial lung disease (ILD) is controversial. Objectives: To evaluate the association between statin use and ILD. Methods: We used regression analyses to evaluate the...

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Hauptverfasser: Xu, Jin-Fu, Washko, George R., Nakahira, Kiichi, Hatabu, Hiroto, Patel, Avignat S., Fernandez, Isis E., Nishino, Mizuki, Okajima, Yuka, Yamashiro, Tsuneo, Ross, James C., San José Estépar, Raúl, Diaz, Alejandro A., Li, Hui-Ping, Qu, Jie-Ming, Himes, Blanca E., Come, Carolyn E., D'Aco, Katherine, Martinez, Fernando J., Han, MeiLan K., Lynch, David A., Crapo, James D., Morse, Danielle, Ryter, Stefan W., Silverman, Edwin K., Rosas, Ivan O., Choi, Augustine M. K., Hunninghake, Gary M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2012
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297101/
https://ncbi.nlm.nih.gov/pubmed/22246178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201108-1574OC
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