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N-carbamylglutamate augments ureagenesis and reduces ammonia and glutamine levels in patients with propionic acidemia

OBJECTIVE: To determine whether N-carbamylglutamate reduces plasma levels of ammonia and glutamine and increases ureagenesis rate in patients with propionic acidemia PATIENTS AND METHODS: Identical four-hour studies were performed before and immediately after a 3-day trial of oral N-carbamylglutamat...

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Bibliografiske detaljer
Main Authors: Mew, Nicholas Ah, McCarter, Robert, Daikhin, Yevgeny, Nissim, Itzhak, Yudkoff, Marc, Tuchman, Mendel
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297024/
https://ncbi.nlm.nih.gov/pubmed/20566609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1542/peds.2010-0008
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