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Selective mGluR1 Antagonist EMQMCM Inhibits the Kainate-Induced Excitotoxicity in Primary Neuronal Cultures and in the Rat Hippocampus

Abundant evidence suggests that indirect inhibitory modulation of glutamatergic transmission, via metabotropic glutamatergic receptors (mGluR), may induce neuroprotection. The present study was designed to determine whether the selective antagonist of mGluR1 (3-ethyl-2-methyl-quinolin-6-yl)-(4-metho...

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Hlavní autoři: Śmiałowska, Maria, Gołembiowska, Krystyna, Kajta, Małgorzata, Zięba, Barbara, Dziubina, Anna, Domin, Helena
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer-Verlag 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296950/
https://ncbi.nlm.nih.gov/pubmed/22144346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12640-011-9293-4
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