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Selective mGluR1 Antagonist EMQMCM Inhibits the Kainate-Induced Excitotoxicity in Primary Neuronal Cultures and in the Rat Hippocampus

Abundant evidence suggests that indirect inhibitory modulation of glutamatergic transmission, via metabotropic glutamatergic receptors (mGluR), may induce neuroprotection. The present study was designed to determine whether the selective antagonist of mGluR1 (3-ethyl-2-methyl-quinolin-6-yl)-(4-metho...

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Detalhes bibliográficos
Main Authors: Śmiałowska, Maria, Gołembiowska, Krystyna, Kajta, Małgorzata, Zięba, Barbara, Dziubina, Anna, Domin, Helena
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296950/
https://ncbi.nlm.nih.gov/pubmed/22144346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12640-011-9293-4
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