Large-scale mapping of human protein interactome using structural complexes

Although the identification of protein interactions by high-throughput (HTP) methods progresses at a fast pace, ‘interactome' data sets still suffer from high rates of false positives and low coverage. To map the human protein interactome, we describe a new framework that uses experimental evid...

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Bibliografiske detaljer
Main Authors: Tyagi, Manoj, Hashimoto, Kosuke, Shoemaker, Benjamin A, Wuchty, Stefan, Panchenko, Anna R
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2012
Fag:
Scientific Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296913/
https://ncbi.nlm.nih.gov/pubmed/22261719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.261
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