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Evolution of JAK-STAT Pathway Components: Mechanisms and Role in Immune System Development

BACKGROUND: Lying downstream of a myriad of cytokine receptors, the Janus kinase (JAK) – Signal transducer and activator of transcription (STAT) pathway is pivotal for the development and function of the immune system, with additional important roles in other biological systems. To gain further insi...

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Detalles Bibliográficos
Main Authors: Liongue, Clifford, O'Sullivan, Lynda A., Trengove, Monique C., Ward, Alister C.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296744/
https://ncbi.nlm.nih.gov/pubmed/22412924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032777
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