Cell Lineage Specific Distribution of H3K27 Trimethylation Accumulation in an In Vitro Model for Human Implantation

Female mammals inactivate one of their two X-chromosomes to compensate for the difference in gene-dosage with males that have just one X-chromosome. X-chromosome inactivation is initiated by the expression of the non-coding RNA Xist, which coats the X-chromosome in cis and triggers gene silencing. I...

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Main Authors: Teklenburg, Gijs, Weimar, Charlotte H. E., Fauser, Bart C. J. M., Macklon, Nick, Geijsen, Niels, Heijnen, Cobi J., Chuva de Sousa Lopes, Susana M., Kuijk, Ewart W.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296731/
https://ncbi.nlm.nih.gov/pubmed/22412909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032701
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