Minocycline modulates antigen-specific CTL activity through inactivation of mononuclear phagocytes in patients with HTLV-I associated neurologic disease

BACKGROUND: The activation of mononuclear phagocytes (MPs), including monocytes, macrophages and dendritic cells, contributes to central nervous system inflammation in various neurological diseases. In HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP), MPs are reservoirs of HTLV-I,...

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Detalhes bibliográficos
Main Authors: Enose-Akahata, Yoshimi, Matsuura, Eiji, Tanaka, Yuetsu, Oh, Unsong, Jacobson, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296610/
https://ncbi.nlm.nih.gov/pubmed/22335964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-9-16
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