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Quinolinic Acid, an Endogenous Molecule Combining Excitotoxicity, Oxidative Stress and Other Toxic Mechanisms

Quinolinic acid (QUIN), an endogenous metabolite of the kynurenine pathway, is involved in several neurological disorders, including Huntington’s disease, Alzheimer’s disease, schizophrenia, HIV associated dementia (HAD) etc. QUIN toxicity involves several mechanisms which trigger various metabolic...

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Detalhes bibliográficos
Main Authors: Pérez-De La Cruz, Verónica, Carrillo-Mora, Paul, Santamaría, Abel
Formato: Artigo
Idioma:Inglês
Publicado em: Libertas Academica 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296489/
https://ncbi.nlm.nih.gov/pubmed/22408367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/IJTR.S8158
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