The Oxygen Free Radicals Originating from Mitochondrial Complex I Contribute to Oxidative Brain Injury Following Hypoxia–Ischemia in Neonatal Mice

Oxidative stress and Ca(2+) toxicity are mechanisms of hypoxic–ischemic (HI) brain injury. This work investigates if partial inhibition of mitochondrial respiratory chain protects HI brain by limiting a generation of oxidative radicals during reperfusion. HI insult was produced in p10 mice treated w...

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Main Authors: Niatsetskaya, Zoya V., Sosunov, Sergei A., Matsiukevich, Dzmitry, Utkina-Sosunova, Irina V., Ratner, Veniamin I., Starkov, Anatoly A., Ten, Vadim S.
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2012
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Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296485/
https://ncbi.nlm.nih.gov/pubmed/22378894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6303-11.2012
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