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Formation of the First Peptide Bond: The Structure of EF-P Bound to the 70S Ribosome

Elongation factor P (EF-P) is an essential protein that stimulates the formation of the first peptide bond in protein synthesis. Here we report the crystal structure of EF-P bound to the Thermus thermophilus 70S ribosome along with the initiator transfer RNA N-formyl-methionyl-tRNA(i) (fMet-tRNA(i)(...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Blaha, Gregor, Stanley, Robin E., Steitz, Thomas A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296453/
https://ncbi.nlm.nih.gov/pubmed/19696344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1175800
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