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Interleukin 1 induces a shock-like state in rabbits. Synergism with tumor necrosis factor and the effect of cyclooxygenase inhibition.

In addition to activating T and B lymphocytes, interleukin 1 (IL-1) induces several hematologic and metabolic changes typical of host responses to infection and injury. We now report a new biological property, namely, the induction of hypotension. Rabbits given a single intravenous injection of reco...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Okusawa, S, Gelfand, J A, Ikejima, T, Connolly, R J, Dinarello, C A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329645/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3258319/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113431
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