Interleukin-1 (IL-1) receptor antagonist prevents Staphylococcus epidermidis-induced hypotension and reduces circulating levels of tumor necrosis factor and IL-1 beta in rabbits.

Similar to shock in gram-negative sepsis, shock from gram-positive organisms is mediated, in part, by tumor necrosis factor (TNF) and interleukin-1 (IL-1). In the present study, rabbits were infused with IL-1 receptor antagonist (IL-1ra) prior to and during Staphylococcus epidermidis-induced hypoten...

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Detalhes bibliográficos
Main Authors: Aiura, K, Gelfand, J A, Burke, J F, Thompson, R C, Dinarello, C A
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC281009/
https://ncbi.nlm.nih.gov/pubmed/8335365
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