Interleukin-1 (IL-1) receptor antagonist prevents Staphylococcus epidermidis-induced hypotension and reduces circulating levels of tumor necrosis factor and IL-1 beta in rabbits.

Similar to shock in gram-negative sepsis, shock from gram-positive organisms is mediated, in part, by tumor necrosis factor (TNF) and interleukin-1 (IL-1). In the present study, rabbits were infused with IL-1 receptor antagonist (IL-1ra) prior to and during Staphylococcus epidermidis-induced hypoten...

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Pubblicato in:	Infect Immun
Autori principali:	Aiura, K, Gelfand, J A, Burke, J F, Thompson, R C, Dinarello, C A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1993
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281009/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8335365/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.61.8.3342-3350.1993
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