Identification of a Minimal Region of the HIV-1 5´-Leader required for RNA Dimerization, NC Binding and Packaging

Assembly of Human Immunodeficiency Virus Type-1 (HIV-1) particles is initiated in the cytoplasm by the formation of a ribonucleoprotein complex comprising the dimeric RNA genome and a small number of viral Gag polyproteins. Genomes are recognized by the nucleocapsid (NC) domains of Gag, which intera...

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Autori principali: Heng, Xiao, Kharytonchyk, Siarhei, Garcia, Eric L., Lu, Kun, Divakaruni, Sai Sachin, LaCotti, Courtney, Edme, Kedy, Telesnitsky, Alice, Summers, Michael F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296369/
https://ncbi.nlm.nih.gov/pubmed/22306406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.01.033
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