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Palladium(II)-Catalyzed Enantioselective Synthesis of 2-Vinyl Oxygen Heterocycles

[Image: see text] 2-Vinylchromanes (1), 2-vinyl-1,4-benzodioxanes (2), and 2,3-dihydro-2-vinyl-2H-1,4-benzoxazines (3) can be prepared in high yields (90–98%) and excellent enantiomeric purities (87–98% ee) by [COP-OAc](2)-catalyzed cyclization of phenolic (E)-allylic trichloroacetimidate precursors...

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Autores principales: Cannon, Jeffrey S., Olson, Angela C., Overman, Larry E., Solomon, Nicole S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296363/
https://ncbi.nlm.nih.gov/pubmed/22316285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo202553a
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