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The potential for BRAF V600 inhibitors in advanced cutaneous melanoma: rationale and latest evidence
Historically, patients with advanced cutaneous melanoma have a poor prognosis and limited treatment options. The discovery of selective v-raf murine sarcoma viral oncogene homolog B1 (BRAF) V600 mutation as an oncogenic mutation in cutaneous melanoma and the importance of the mitogen-activated prote...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
SAGE Publications
2012
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3296083/ https://ncbi.nlm.nih.gov/pubmed/22423265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758834011432949 |
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