Gram-negative bacteremia produces both severe systolic and diastolic cardiac dysfunction in a canine model that simulates human septic shock.

A canine sepsis model that simulates the human cardiovascular response to septic shock was produced in 10 conscious unsedated dogs by implanting an Escherichia coli-infected clot into the peritoneum, resulting in bacteremia. By employing serial, simultaneous measurements of radionuclide scan-determi...

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Pubblicato in:	J Clin Invest
Autori principali:	Natanson, C, Fink, M P, Ballantyne, H K, MacVittie, T J, Conklin, J J, Parrillo, J E
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1986
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329557/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3722379/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112559
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