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Gram-negative bacteremia produces both severe systolic and diastolic cardiac dysfunction in a canine model that simulates human septic shock.

A canine sepsis model that simulates the human cardiovascular response to septic shock was produced in 10 conscious unsedated dogs by implanting an Escherichia coli-infected clot into the peritoneum, resulting in bacteremia. By employing serial, simultaneous measurements of radionuclide scan-determi...

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Udgivet i:J Clin Invest
Principais autores: Natanson, C, Fink, M P, Ballantyne, H K, MacVittie, T J, Conklin, J J, Parrillo, J E
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1986
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329557/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3722379/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112559
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