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Localization of the binding site of tissue-type plasminogen activator to fibrin.

Functionally active A and B chains were separated from a two-chain form of recombinant tissue-type plasminogen activator after mild reduction and alkylation. The A chain was found to be responsible for the binding to lysine-Sepharose or fibrin and the B chain contained the catalytic activity of tiss...

詳細記述

保存先:
書誌詳細
出版年:J Clin Invest
主要な著者: Ichinose, A, Takio, K, Fujikawa, K
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 1986
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329545/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3088041/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112546
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