Antigenic diversity is generated by distinct evolutionary mechanisms in African trypanosome species

Antigenic variation enables pathogens to avoid the host immune response by continual switching of surface proteins. The protozoan blood parasite Trypanosoma brucei causes human African trypanosomiasis (“sleeping sickness”) across sub-Saharan Africa and is a model system for antigenic variation, surv...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Jackson, Andrew P., Berry, Andrew, Aslett, Martin, Allison, Harriet C., Burton, Peter, Vavrova-Anderson, Jana, Brown, Robert, Browne, Hilary, Corton, Nicola, Hauser, Heidi, Gamble, John, Gilderthorp, Ruth, Marcello, Lucio, McQuillan, Jacqueline, Otto, Thomas D., Quail, Michael A., Sanders, Mandy J., van Tonder, Andries, Ginger, Michael L., Field, Mark C., Barry, J. David, Hertz-Fowler, Christiane, Berriman, Matthew
التنسيق: Artigo
اللغة:Inglês
منشور في: National Academy of Sciences 2012
الموضوعات:
Biological Sciences
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295286/
https://ncbi.nlm.nih.gov/pubmed/22331916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117313109
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