Antigenic diversity is generated by distinct evolutionary mechanisms in African trypanosome species

Antigenic variation enables pathogens to avoid the host immune response by continual switching of surface proteins. The protozoan blood parasite Trypanosoma brucei causes human African trypanosomiasis (“sleeping sickness”) across sub-Saharan Africa and is a model system for antigenic variation, surv...

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Detalhes bibliográficos
Main Authors: Jackson, Andrew P., Berry, Andrew, Aslett, Martin, Allison, Harriet C., Burton, Peter, Vavrova-Anderson, Jana, Brown, Robert, Browne, Hilary, Corton, Nicola, Hauser, Heidi, Gamble, John, Gilderthorp, Ruth, Marcello, Lucio, McQuillan, Jacqueline, Otto, Thomas D., Quail, Michael A., Sanders, Mandy J., van Tonder, Andries, Ginger, Michael L., Field, Mark C., Barry, J. David, Hertz-Fowler, Christiane, Berriman, Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295286/
https://ncbi.nlm.nih.gov/pubmed/22331916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117313109
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