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Impaired nuclear responsiveness to cytoplasmic signals in lymphocytes from elderly humans with depressed proliferative responses.

Lymphocytes from many elderly individuals exhibit depressed proliferative responses to the plant phytohemagglutinin (PHA). We have previously reported that this proliferative defect is not due to a failure to generate a cytoplasmic activator of DNA replication (ADR). In the present study, we tested...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gutowski, J K, Innes, J B, Weksler, M E, Cohen, S
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1986
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC329528/
https://ncbi.nlm.nih.gov/pubmed/3722382
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