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Impaired nuclear responsiveness to cytoplasmic signals in lymphocytes from elderly humans with depressed proliferative responses.

Lymphocytes from many elderly individuals exhibit depressed proliferative responses to the plant phytohemagglutinin (PHA). We have previously reported that this proliferative defect is not due to a failure to generate a cytoplasmic activator of DNA replication (ADR). In the present study, we tested...

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Detaylı Bibliyografya
Yayımlandı:J Clin Invest
Asıl Yazarlar: Gutowski, J K, Innes, J B, Weksler, M E, Cohen, S
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 1986
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329528/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3722382/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112570
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