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“True” Antiandrogens—Selective Non-Ligand-Binding Pocket Disruptors of Androgen Receptor–Coactivator Interactions: Novel Tools for Prostate Cancer
[Image: see text] Prostate cancer (PCa) therapy typically involves administration of “classical” antiandrogens, competitive inhibitors of androgen receptor (AR) ligands, dihydrotestosterone (DHT) and testosterone (tes), for the ligand-binding pocket (LBP) in the ligand-binding domain (LBD) of AR. Pr...
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| Główni autorzy: | , , , , , , , , |
|---|---|
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Chemical
Society
2012
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| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3295204/ https://ncbi.nlm.nih.gov/pubmed/22280402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm201438f |
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