Genetic Analyses Reveal Differences in the VP7 and VP4 Antigenic Epitopes between Human Rotaviruses Circulating in Belgium and Rotaviruses in Rotarix and RotaTeq

Two live-attenuated rotavirus group A (RVA) vaccines, Rotarix (G1P[8]) and RotaTeq (G1-G4, P[8]), have been successfully introduced in many countries worldwide, including Belgium. The parental RVA strains used to generate the vaccines were isolated more than 20 years ago in France (G4 parental strai...

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Detalhes bibliográficos
Main Authors: Zeller, Mark, Patton, John T., Heylen, Elisabeth, De Coster, Sarah, Ciarlet, Max, Van Ranst, Marc, Matthijnssens, Jelle
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Virology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295124/
https://ncbi.nlm.nih.gov/pubmed/22189107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.05590-11
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