Genetic Analyses Reveal Differences in the VP7 and VP4 Antigenic Epitopes between Human Rotaviruses Circulating in Belgium and Rotaviruses in Rotarix and RotaTeq

Two live-attenuated rotavirus group A (RVA) vaccines, Rotarix (G1P[8]) and RotaTeq (G1-G4, P[8]), have been successfully introduced in many countries worldwide, including Belgium. The parental RVA strains used to generate the vaccines were isolated more than 20 years ago in France (G4 parental strai...

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Autors principals: Zeller, Mark, Patton, John T., Heylen, Elisabeth, De Coster, Sarah, Ciarlet, Max, Van Ranst, Marc, Matthijnssens, Jelle
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
Matèries:
Virology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295124/
https://ncbi.nlm.nih.gov/pubmed/22189107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.05590-11
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