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Genetic Analyses Reveal Differences in the VP7 and VP4 Antigenic Epitopes between Human Rotaviruses Circulating in Belgium and Rotaviruses in Rotarix and RotaTeq

Two live-attenuated rotavirus group A (RVA) vaccines, Rotarix (G1P[8]) and RotaTeq (G1-G4, P[8]), have been successfully introduced in many countries worldwide, including Belgium. The parental RVA strains used to generate the vaccines were isolated more than 20 years ago in France (G4 parental strai...

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Bibliografiske detaljer
Main Authors: Zeller, Mark, Patton, John T., Heylen, Elisabeth, De Coster, Sarah, Ciarlet, Max, Van Ranst, Marc, Matthijnssens, Jelle
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295124/
https://ncbi.nlm.nih.gov/pubmed/22189107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.05590-11
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