Cyclic AMP-Dependent Protein Kinase Catalytic Subunits Have Divergent Roles in Virulence Factor Production in Two Varieties of the Fungal Pathogen Cryptococcus neoformans

Our earlier findings established that cyclic AMP-dependent protein kinase functions in a signaling cascade that regulates mating and virulence of Cryptococcus neoformans var. grubii (serotype A). Mutants lacking the serotype A protein kinase A (PKA) catalytic subunit Pka1 are unable to mate, fail to...

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Main Authors: Hicks, Julie K., D'Souza, Cletus A., Cox, Gary M., Heitman, Joseph
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2004
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC329511/
https://ncbi.nlm.nih.gov/pubmed/14871933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.3.1.14-26.2004
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