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Dietary Restriction and Aging in Rodents: a Current View on its Molecular Mechanisms

Dietary restriction (DR) is a robust non-genetic intervention that reduces morbidity and mortality in a range of organisms. This suggests the presence of an evolutionary-conserved pathway that regulates aging and lifespan in response to reduced food or energy intake. Recent genetic analyses have sho...

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Autors principals: Shimokawa, Isao, Trindade, Lucas S.
Format: Artigo
Idioma:Inglês
Publicat: JKL International LLC 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295025/
https://ncbi.nlm.nih.gov/pubmed/22396859
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