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Identification of New Antileishmanial Leads from Hits Obtained by High-Throughput Screening
A previous screen of ∼200,000 compounds from the PubChem database identified 70 compounds possessing 50% effective concentrations (EC(50)s) below 1 μM against Leishmania major promastigotes that were not toxic to mammalian epithelial cancer cells at this concentration (E. Sharlow et al., PLoS Negl....
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3294885/ https://ncbi.nlm.nih.gov/pubmed/22143523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05412-11 |
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