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Mutations at Several Loci Cause Increased Expression of Ribonucleotide Reductase in Escherichia coli

Production of deoxyribonucleotides for DNA synthesis is an essential and tightly regulated process. The class Ia ribonucleotide reductase (RNR), the product of the nrdAB genes, is required for aerobic growth of Escherichia coli. In catalyzing the reduction of ribonucleotides, two of the cysteines of...

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Autori principali: Feeney, Morgan Anne, Ke, Na, Beckwith, Jon
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294829/
https://ncbi.nlm.nih.gov/pubmed/22247510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.05989-11
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