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Mutations at Several Loci Cause Increased Expression of Ribonucleotide Reductase in Escherichia coli

Production of deoxyribonucleotides for DNA synthesis is an essential and tightly regulated process. The class Ia ribonucleotide reductase (RNR), the product of the nrdAB genes, is required for aerobic growth of Escherichia coli. In catalyzing the reduction of ribonucleotides, two of the cysteines of...

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Detalhes bibliográficos
Main Authors: Feeney, Morgan Anne, Ke, Na, Beckwith, Jon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294829/
https://ncbi.nlm.nih.gov/pubmed/22247510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.05989-11
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