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Glutamate Dehydrogenase Affects Resistance to Cell Wall Antibiotics in Bacillus subtilis
The glutamate dehydrogenase RocG of Bacillus subtilis is a bifunctional protein with both enzymatic and regulatory functions. Here we show that the rocG null mutant is sensitive to β-lactams, including cefuroxime (CEF), and to fosfomycin but that resistant mutants arise due to gain-of-function mutat...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3294759/ https://ncbi.nlm.nih.gov/pubmed/22178969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.06547-11 |
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