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The Antibacterial Activity of LL-37 against Treponema denticola Is Dentilisin Protease Independent and Facilitated by the Major Outer Sheath Protein Virulence Factor

Host defense peptides are innate immune effectors that possess both bactericidal activities and immunomodulatory functions. Deficiency in the human host defense peptide LL-37 has previously been correlated with severe periodontal disease. Treponema denticola is an oral anaerobic spirochete closely a...

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Autors principals: Rosen, Graciela, Sela, Michael N., Bachrach, Gilad
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294656/
https://ncbi.nlm.nih.gov/pubmed/22184422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05903-11
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