The Antibacterial Activity of LL-37 against Treponema denticola Is Dentilisin Protease Independent and Facilitated by the Major Outer Sheath Protein Virulence Factor

Host defense peptides are innate immune effectors that possess both bactericidal activities and immunomodulatory functions. Deficiency in the human host defense peptide LL-37 has previously been correlated with severe periodontal disease. Treponema denticola is an oral anaerobic spirochete closely a...

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Bibliographic Details
Main Authors: Rosen, Graciela, Sela, Michael N., Bachrach, Gilad
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Bacterial Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294656/
https://ncbi.nlm.nih.gov/pubmed/22184422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05903-11
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