Conserved and Variant Epitopes of Plasmodium vivax Duffy Binding Protein as Targets of Inhibitory Monoclonal Antibodies

The Duffy binding protein (DBP) is a vital ligand for Plasmodium vivax blood-stage merozoite invasion, making the molecule an attractive vaccine candidate against vivax malaria. Similar to other blood-stage vaccine candidates, DBP allelic variation eliciting a strain-specific immunity may be a major...

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Hlavní autoři: Ntumngia, Francis B., Schloegel, Jesse, Barnes, Samantha J., McHenry, Amy M., Singh, Sanjay, King, Christopher L., Adams, John H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
Témata:
Microbial Immunity and Vaccines
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294652/
https://ncbi.nlm.nih.gov/pubmed/22215740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05924-11
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