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Elements which stimulate gene amplification in mammalian cells: role of recombinogenic sequences/structures and transcriptional activation.

HSAG-1 is a 3.4 kb mammalian genomic element which has been shown to stimulate the amplification of the pSV2DHFR expression vector in cis when transfected into a variety of cell lines (1). This amplification stimulatory activity requires the interaction of multiple positive acting elements that incl...

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Bibliographic Details
Main Authors: McArthur, J G, Beitel, L K, Chamberlain, J W, Stanners, C P
Format: Artigo
Language:Inglês
Published: 1991
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC329460/
https://ncbi.nlm.nih.gov/pubmed/2041783
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